Keeping it local: Protecting the brain starts at the synapse
New research by scientists at UC San Francisco shows that one of the brain’s fundamental self-protection mechanisms depends on coordinated, finely calibrated teamwork among neurons and non-neural cells knows as glial cells, which until fairly recently were thought to be mere support cells for neurons. The study, which has implications for understanding neurodegenerative diseases, stroke, and other nervous system disorders, adds to a growing body of evidence that glial cells are integral to brain function.
Because this mechanism is localized at synapses, the sites where communication between neurons takes place, said Marta Margeta, MD, PhD, assistant professor of pathology and senior author of the new study, it ensures that protective measures will only be taken when and where they’re most needed.
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Keeping it local: Protecting the brain starts at the synapse

New research by scientists at UC San Francisco shows that one of the brain’s fundamental self-protection mechanisms depends on coordinated, finely calibrated teamwork among neurons and non-neural cells knows as glial cells, which until fairly recently were thought to be mere support cells for neurons. The study, which has implications for understanding neurodegenerative diseases, stroke, and other nervous system disorders, adds to a growing body of evidence that glial cells are integral to brain function.

Because this mechanism is localized at , the sites where communication between neurons takes place, said Marta Margeta, MD, PhD, assistant professor of pathology and senior author of the new study, it ensures that protective measures will only be taken when and where they’re most needed.

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