Mutations Pervade Mitochondrial DNA
Pathogenic mutations in mitochondrial DNA are common in healthy people, according to a new study.
Mutations in one or more copies of mitochondrial DNA, known as heteroplasmies, are likely to be much more common in healthy people than previously anticipated. Approximately 90 percent of healthy participants in the 1000 Genomes Project harbored at least one heteroplasmy, and 20 percent bore mitochondrial genome mutations implicated in diseases, according to the results of a study published today (July 7) in PNAS.
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Mutations Pervade Mitochondrial DNA

Pathogenic mutations in mitochondrial DNA are common in healthy people, according to a new study.

Mutations in one or more copies of mitochondrial DNA, known as heteroplasmies, are likely to be much more common in healthy people than previously anticipated. Approximately 90 percent of healthy participants in the 1000 Genomes Project harbored at least one heteroplasmy, and 20 percent bore mitochondrial genome mutations implicated in diseases, according to the results of a study published today (July 7) in PNAS.

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